Intracellular trafficking of diphtheria toxin and its mutated form, CRM197, in the endocytic pathway

Tarih
2018
Yazar
Edis, Bilge Ozerman
Bektas, Muhammet
Varol, Basak
Haciosmanoglu, Ebru
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Özet
OBJECTIVE: Diphtheria toxin (DTx) is a well-characterized bacterial toxin. However, the endocytic pathway of the mutant of DTx, CRM197, which is used as an immunological adjuvant, has not yet been fully explained. The aim of this study was to investigate the intracellular trafficking of CRM197-loaded endosomes.
Bağlantı
http://hdl.handle.net/20.500.12627/160016
https://doi.org/10.14744/nci.2017.55798
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