Intracellular trafficking of diphtheria toxin and its mutated form, CRM197, in the endocytic pathway

Date
2018
Author
Edis, Bilge Ozerman
Bektas, Muhammet
Varol, Basak
Haciosmanoglu, Ebru
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Abstract
OBJECTIVE: Diphtheria toxin (DTx) is a well-characterized bacterial toxin. However, the endocytic pathway of the mutant of DTx, CRM197, which is used as an immunological adjuvant, has not yet been fully explained. The aim of this study was to investigate the intracellular trafficking of CRM197-loaded endosomes.
URI
http://hdl.handle.net/20.500.12627/160016
https://doi.org/10.14744/nci.2017.55798
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