Preclinical Evaluation of F-18-ML-10 to Determine Timing of Apoptotic Response to Chemotherapy in Solid Tumors
Author
DeBlasio, Nicole
Mason, N. Scott
Anderson, Carolyn J.
Mountz, James M.
Ocak, Meltem
Demirci, Emre
Ahmed, Rafay
Latoche, Joseph
Radelet, April
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Purpose: We investigated 2-(5-fluoro-pentyl)-2-methyl-malonic acid (F-18-ML-10) positron emission tomography (PET) imaging of apoptosis posttherapy to determine optimal timing for predicting chemotherapy response in a mouse head/neck xenograft cancer model.
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