Local Renin-Angiotensin System in Normal Hematopoietic and Multiple Myeloma-Related Progenitor Cells

Date
2014
Author
BÜYÜKAŞIK, YAHYA
Sayitoglu, Müge
AKSU, SALİH
SAYINALP, NİLGÜN
Hatirnaz, Ozden
GÖKER, HAKAN
ÖZCEBE, OSMAN İLHAMİ
Ozbek, Ugur
Haznedaroglu, Ibrahim C.
Uz, Burak
Tatonyan, Suzin Catal
Erbilgin, Yucel
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Abstract
Objective: The prominent functions of the local renin-angiotensin system (RAS) in primitive hematopoiesis further support the hypothesis that local autocrine bone marrow RAS could also be active in neoplastic hematopoiesis. The aim of this study is to examine critical RAS elements in normal CD34+ hematopoietic stem cells and multiple myeloma (MM)-related progenitor cells.
URI
http://hdl.handle.net/20.500.12627/96479
https://doi.org/10.4274/tjh.2013.0011
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