Primary cutaneous follicle center lymphoma responsive to interferon alfa-2a

Abstract

Follicular lymphoma is the most common type of primary cutaneous B-cell lymphomas with a predilection for the scalp, forehead, and trunk. Herein we report a case of primary cutaneous follicle center lymphoma on the scalp of 72-year-old female. The diagnosis was made histopathologically, confirming the presence of centrocytes and centroblasts. Complete resolution was achieved following administration of subcutaneous interferon alpha-2a at a dose of 4.5 x 10(6) IU three times weekly for 3 months.