Subthreshold depression in patients with Parkinson's disease and dementia - clinical and demographic correlates

Abstract

Background About 40% of the patients with Parkinson's disease (PD) have depressive symptoms, either major depression (MD) or subthreshold depression. Depression was found to be associated with age and age at onset of PD, female gender, more severe parkinsonism, in particular with left-sided and akinetic-ligid symptoms, more functional impairment and cognitive impairment.