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CIRCULATING MONOCYTE CHEMOATTRACTANT PROTEIN-1 (MCP-1/CCL-2) AS A POTENTIAL BIOMARKER FOR THE DIAGNOSIS OF PANCREATIC ADENOCARCINOMA

Date
2017
Author
Binboga, Sinan
Karabulut, Senem
Alis, Halil
Aykan, Nuri Faruk
Bilgin, Elif
Afsar, Cigdem Usul
Karabulut, Mehmet
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Abstract
Introduction: Pancreatic cancer is a highly lethal malignancy. Chemokines may control the macrophage infiltrate found in many solid tumors. Monocyte chemoattractant protein-1 (MCP-1/CCL2) plays a key role in the recruitment and activation of monocytes during inflammation. MCP-1 is a small chemotactic protein that has been found in several kinds of tumor tissue samples and functions as a key regulator of cancer progression. This study was conducted to investigate the serum levels of MCP-1 in patients with pancreatic adenocarcinoma (PA) and the relationship with tumor progression and known prognostic parameters.
URI
http://hdl.handle.net/20.500.12627/87343
https://doi.org/10.19193/0393-6384_2017_3_075
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Creative Commons Lisansı

İstanbul Üniversitesi Akademik Arşiv Sistemi (ilgili içerikte aksi belirtilmediği sürece) Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

DSpace software copyright © 2002-2016  DuraSpace
Contact Us | Send Feedback
Theme by 
Atmire NV