Study for the Diagnostic Screening of Paroxysmal Nocturnal Hemoglobinuria in Older Patients with Unexplained Anemia and/or Cytopenia

Date
2020
Author
ÜNAL, ALİ
Ozdemir, Zehra N.
İLHAN, OSMAN
Ozet, Gulsum
Falay, Mesude
Tuglular, Tulin
Turgut, Mehmet
GÜVENÇ, BİROL
Ayyildiz, Orhan
ANDIÇ, NESLİHAN
Hacihanefioglu, Abdullah
ŞAHİN, FAHRİ
ŞENCAN, MEHMET
ALİ, RIDVAN
ÖZSAN, GÜNER HAYRİ
Yildirim, Rahsan
TİFTİK, EYÜP NACİ
TOMBAK, ANIL
SALİM, OZAN
KAYA, EMİN
Akay, Olga M.
Okan, Vahap
PEHLİVAN, MUSTAFA
SAYDAM, GÜRAY
Yenerel, Mustafa Nuri
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Abstract
Background: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematopoietic stem cell disease that may lead to weakness and death of patients, if unrecognized and untreated. Although consensus guidelines were reviewed recently for the diagnostic screening of PNH with multi-parameter flow cytometry (FCM), until now, no study has investigated the efficiency of such clinical indications in older patients.
URI
http://hdl.handle.net/20.500.12627/86768
https://doi.org/10.7754/clin.lab.2020.191218
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