SERUM AKT2 LEVELS AS A MARKER FOR LUNG CANCER

Abstract

Introduction: AKT overexpression has shown in some cancer types such as breast, prostate, ovarian and gastric cancer (1, 2, 3). Due to conflicting results reported in recent studies investigating the phosphoinositide-3-kinase-protein kinase (PI3K) signal transduction pathway and lung cancer, we know AKT2 plays a critical role (4). The aim of our study is to investigate whether circulating AKT2 levels have diagnostic, predictive and prognostic role in lung cancer.