Reduced Gray Matter Volume in the Frontotemporal Cortex of Patients with Early Subacute Sclerosing Panencephalitis

Abstract

BACKGROUND AND PURPOSE: Subacute sclerosing pariencephalitis (SSPE) is a persistent infection of the central nervous system by the measles virus. Patients in the initial stages of SSPE show behavioral symptoms and usually normal cranial MR imaging findings. We aimed to investigate the gray matter volume changes in patients with early SSPE.