An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype
Date
2017Author
Gordon, Scott D.
Milaneschi, Yuri
Montgomery, Grant W.
Mors, Ole
Mosley, Thomas H.
Murabito, Joanne M.
Mueller-Myhsok, Bertram
Nothen, Markus M.
Nyholt, Dale R.
O'Donovan, Michael C.
Penninx, Brenda W.
Pergadia, Michele L.
Perlis, Roy
Potash, James B.
Preisig, Martin
Purcell, Shaun M.
Quiroz, Jorge A.
Raikkonen, Katri
Rice, John P.
Rietschel, Marcella
Rivera, Margarita
Schulze, Thomas G.
Shi, Jianxin
Shyn, Stanley
Sinnamon, Grant C.
Smit, Johannes H.
Smoller, Jordan W.
Snieder, Harold
Tanaka, Toshiko
Tansey, Katherine E.
Teumer, Alexander
Uher, Rudolf
Umbricht, Daniel
Van der Auwera, Sandra
Ware, Erin B.
Weir, David R.
Weissman, Myrna M.
Willemsen, Gonneke
Yang, Jingyun
Zhao, Wei
Tiemeier, Henning
Sullivan, Patrick F.
Direk, Neşe
Williams, Stephanie
Smith, Jennifer A.
Ripke, Stephan
Air, Tracy
Amare, Azmeraw T.
Amin, Najaf
Baune, Bernhard T.
Bennett, David A.
Blackwood, Douglas H. R.
Boomsma, Dorret
Breen, Gerome
Buttenschon, Henriette N.
Byrne, Enda M.
Borglum, Anders D.
Castelao, Enrique
Cichon, Sven
Clarke, Toni-Kim
Cornelis, Marilyn C.
Dannlowski, Udo
De Jager, Philip L.
Demirkan, Ayse
Domenici, Enrico
van Duijn, Cornelia M.
Dunn, Erin C.
Eriksson, Johan G.
Esko, Tonu
Faul, Jessica D.
Ferrucci, Luigi
Fornage, Myriam
de Geus, Eco
Gill, Michael
Grabe, Hans Joergen
van Grootheest, Gerard
Hamilton, Steven P.
Hartman, Catharina A.
Heath, Andrew C.
Hek, Karin
Hofman, Albert
Homuth, Georg
Horn, Carsten
Hottenga, Jouke Jan
Kardia, Sharon L. R.
Kloiber, Stefan
Koenen, Karestan
Kutalik, Zoltan
Ladwig, Karl-Heinz
Lahti, Jari
Levinson, Douglas F.
Lewis, Cathryn M.
Lewis, Glyn
Li, Qingqin S.
Llewellyn, David J.
Lucae, Susanne
Lunetta, Kathryn L.
MacIntyre, Donald J.
Madden, Pamela
Martin, Nicholas G.
McIntosh, Andrew M.
Metspalu, Andres
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Show full item recordAbstract
BACKGROUND: The genetics of depression has been explored in genome-wide association studies that focused on either major depressive disorder or depressive symptoms with mostly negative findings. A broad depression phenotype including both phenotypes has not been tested previously using a genome-wide association approach. We aimed to identify genetic polymorphisms significantly associated with a broad phenotype from depressive symptoms to major depressive disorder.
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