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Antimicrobial activity of some 2-and 3-pyridinyl-1H-benzimidazoles and their Fe-III, Cu-II, Zn-II, and Ag-I complexes

Date
2003
Author
OTUK, Gülten
TAVMAN, Aydın
Ulkuseven, Bahri
BIRTEKSOZ, S
Metadata
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Abstract
2-(2-Pyridinyl)- (L-I), 2-(6-methyl-2-pyridinyl)-(L-II),2-(6-methyl-2-pyridinyl)-5-methyl-(L-III), 2-(3-pyridinyl)- (L-IV), 2-(3-pyridinyl)-5-methyl-1H-benzimidazoles (L-V) and their complexes with Fe(NO3)(3), Cu(NO3)(2), Zn(NO3)(2), and AgNO3 were synthesized and antibacterial activity of the compounds was tested toward Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi, Shigella flexneri, Proteus mirabilis and antifungal activity against Candida albicans. The methyl groups of L-III increase the antimicrobial activity. The Ag-I complexes have considerable activity toward the microorganisms. Some Zn-II complexes show an antimicrobial effect against S. aureus and S. flexneri, although the ligands themselves have no effect. Cull complexes have a considerable antibacterial effect to S. aureus and S. epidermidis.
URI
http://hdl.handle.net/20.500.12627/62010
https://doi.org/10.1007/bf02931328
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Creative Commons Lisansı

İstanbul Üniversitesi Akademik Arşiv Sistemi (ilgili içerikte aksi belirtilmediği sürece) Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

DSpace software copyright © 2002-2016  DuraSpace
Contact Us | Send Feedback
Theme by 
Atmire NV