HLA-DRB1*15 and pediatric aplastic anemia

Tarih
2002
Yazar
Diler, AS
Dorak, MT
Yalman, N
Oguz, R
Anak, S
Oguz, FS
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Özet
We report a positive association between HLA-DRB1*15 (p = 0.0002) in Turkish patients with pediatric severe aplastic anemia (SAA) and a paradoxically favorable influence of the susceptibility marker on the clinical response to immunosuppressive therapy. These findings point to an immune mechanism mediated by DRB1*15 in SAA which confers responsiveness to treatment.
Bağlantı
http://hdl.handle.net/20.500.12627/57482
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