Association between polymorphisms of DNA repair genes and risk of type 2 diabetes mellitus in the Turkish population

Date
2018
Author
Yilmaz, Umit
Yurdum, Leman Melis
Yigitbasi, Nihal
Zeybek, Sakir Umit
Ergen, Hayriye Arzu
Karaali, Zeynep
Yilmaz, Nesibe
Tokmak, Neslihan
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Abstract
Objectives: DNA repair mechanisms work insufficiently in T2DM patients and hyperglycemia seen in diabetes disturbs the oxidant-antioxidant balance thus cause oxidative damage on DNA. The effects of the DNA repair genes' have not yet been investigated on diabetes. The aim of this study was to investigate the association between APE1 Asp148Glu and XPG Asp1104His polymorphisms with T2DM in the Turkish population.
URI
http://hdl.handle.net/20.500.12627/52868
https://doi.org/10.1515/tjb-2016-0107
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