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dc.contributor.authorOzkok, Ahmet
dc.contributor.authorTamcelik, Nevbahar
dc.contributor.authorSarici, Ahmet M.
dc.contributor.authorCicik, Erdogan
dc.contributor.authorOzdamar, Akif
dc.date.accessioned2021-03-03T17:08:08Z
dc.date.available2021-03-03T17:08:08Z
dc.date.issued2013
dc.identifier.citationOzkok A., Tamcelik N., Ozdamar A., Sarici A. M. , Cicik E., "Corneal Viscoelastic Differences Between Pseudoexfoliative Glaucoma and Primary Open-angle Glaucoma", JOURNAL OF GLAUCOMA, cilt.22, sa.9, ss.740-745, 2013
dc.identifier.issn1057-0829
dc.identifier.otherav_48236144-469a-473a-875c-3c43ddd591aa
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/52009
dc.identifier.urihttps://doi.org/10.1097/ijg.0000000000000036
dc.description.abstractPurpose:The aims of this study were to assess the biomechanical properties of corneas with pseudoexfoliative glaucoma (PEXG) and to compare them with those of patients with primary open-angle glaucoma (POAG).Methods:This prospective, comparative case series consisted of 73 eyes of 73 patients, 35 eyes with PEXG (PEXG group) and 38 eyes with POAG (POAG group). Corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOPCC), and Goldmann-correlated intraocular pressure (IOPG) were determined by using ocular response analyzer (ORA). IOP using Goldmann applanation tonometer (GAT) and ultrasonic central corneal thickness (CCT) were also measured for each eye. Exclusion criteria included refractive error/astigmatism of >3.00 D, history of intraocular surgery, corneal disease, angle-closure glaucoma, and secondary glaucoma other than PEXG. In cases where both eyes were eligible, the right eye was preferred for analysis. The main outcome measures were CH, CRF, IOPCC, IOPG, and GAT. The results were statistically analyzed by using t test, general linear model, and the Pearson correlation test.Results:The mean CH was found to be significantly lower in patients with PEXG (8.81.4 mm Hg) than those with primary open-angle glaucoma (9.9 +/- 1.2 mm Hg; P=0.0007). The mean CRF was found to be significantly lower in patients with PEXG (9.5 +/- 1.8 mm Hg) than those with POAG (11.1 +/- 1.3 mm Hg; P<0.0001). IOPCC was not significantly different between the groups (PEXG, 16.7 +/- 2.5 mm Hg; POAG, 16.9 +/- 2.4 mm Hg; P=0.72). IOPG was significantly lower in PEXG group (14.7 +/- 2.7 mm Hg) compared with the POAG group (16.5 +/- 2.5 mm Hg; P=0.004). GAT was significantly lower in the PEXG group (14.6 +/- 2.7 mm Hg) compared with the POAG group (16.4 +/- 2.8 mm Hg; P=0.007). There was no significant difference between the groups regarding mean CCT (PEXG, 546.1 +/- 34.9 ; POAG, 549.1 +/- 25 ; P=0.66) and mean age (PEXG, 70.3 +/- 8.2; POAG, 67.6 +/- 8.8; P=0.17). The difference between the IOPCC and the GAT was 2.1 and 0.5 mm Hg in both PEXG and POAG groups, respectively.Conclusions:Patients with PEXG had lower CH and CRF values than those with POAG. These findings require further investigation to assess the role of differing corneal biomechanical properties between the 2 groups and its association with poor prognosis among patients with PEXG.
dc.language.isoeng
dc.subjectGöz Hastalıkları ve Cerrahisi
dc.subjectCerrahi Tıp Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectOFTALMOLOJİ
dc.titleCorneal Viscoelastic Differences Between Pseudoexfoliative Glaucoma and Primary Open-angle Glaucoma
dc.typeMakale
dc.relation.journalJOURNAL OF GLAUCOMA
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume22
dc.identifier.issue9
dc.identifier.startpage740
dc.identifier.endpage745
dc.contributor.firstauthorID16217


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