Effect of Carnosine on Renal Function, Oxidation and Glycation Products in the Kidneys of High-Fat Diet/Streptozotocin-Induced Diabetic Rats

Uysal, Mujdat; Bingul, Ilknur; Kucukgergin, Canan; Aydin, Abdurrahman Fatih; Dogan-Ekici, Isin; Dogru-Abbasoglu, Semra

Date

2017

Author

Uysal, Mujdat

Bingul, Ilknur

Kucukgergin, Canan

Aydin, Abdurrahman Fatih

Dogan-Ekici, Isin

Dogru-Abbasoglu, Semra

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Abstract

Background High fat diet (HFD) and low dose of streptozotocin (STZ)-treated rats provide an animal model for type 2 Diabetes Mellitus (T2DM). Oxidative stress plays a role in the development of diabetic complications. Carnosine (CAR) has antioxidant and antiglycating properties. We investigated effects of CAR on renal function, oxidation and glycation products in HFD + STZ-rats.

URI

http://hdl.handle.net/20.500.12627/48610
https://doi.org/10.1055/s-0043-100117

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