Combination hyperbaric oxygen and temozolomide therapy in c6 rat glioma model

Date
2012
Author
BOZKURT, Erol Rustu
Bilir, Ayhan
Karaca, Ismail
YAGMURLU, Kaan
OZAR, Engin
DAGISTAN, Yasar
Toklu, Akin
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Abstract
PURPOSE: Temozolomide (TMZ) has anti-tumor activity in patients with malignant glioma. Hyperbaric oxygen (HBO) may enhance the efficacy of certain therapies that are limited because of the hypoxic tumor microenvironment. We examined the combined effects of TMZ-HBO in a rat glioma model.
URI
http://hdl.handle.net/20.500.12627/48418
https://doi.org/10.1590/s0102-86502012000600005
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