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Behcet's syndrome: Facts and controversies

Date
2013
Author
Sevim, Aysegul
Yurdakul, Sebahattin
Tuzun, Yalçın
Ozyazgan, Yilmaz
Mat, Cem
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Abstract
Behcet's syndrome is a systemic vasculitis of small and large vessels affecting both veins and arteries. Almost all patients with Behcet's syndrome have recurrent oral aphthae, followed by genital ulcers, variable skin lesions, such as erythema nodosum and papulopustuler lesions, arthritis, uveitis, thrombophlebitis, and gastrointestinal and central nervous system involvement Recent epidemiologic works suggest that genetic factors are more important than environmental factors in its pathogenesis. European League Against Rheumatism guidelines were recently published for the treatment of Behcet's syndrome. Although these are quite useful for the management of mucocutaneous, eye, and joint involvement, treatment of vascular, neurological, and gastrointestinal involvement are still problematic as there are no controlled studies for these manifestations. This contribution addresses the epidemiology, mucocutaneous manifestations, diagnostic criteria, and evidence-based therapies, including biologic agents. (C) 2013 Elsevier Inc. All rights reserved.
URI
http://hdl.handle.net/20.500.12627/44591
https://doi.org/10.1016/j.clindermatol.2013.01.002
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Creative Commons Lisansı

İstanbul Üniversitesi Akademik Arşiv Sistemi (ilgili içerikte aksi belirtilmediği sürece) Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

DSpace software copyright © 2002-2016  DuraSpace
Contact Us | Send Feedback
Theme by 
Atmire NV