Association between bactericidal/permeability increasing protein (BPI) gene polymorphism (Lys216Glu) and inflammatory bowel disease

Date
2011
Author
Imeryuz, Nese
Hamzaoglu, Ismail
Tahan, Veysel
Tozun, Nurdan
Hamzaoglu, Hulya Over
Akin, Hakan
Tahan, Gulgun
Ture, Filiz
EREN, FATİH
ATUĞ, ÖZLEN
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Abstract
Background: Increasing Increasing evidence suggests that innate immune system may have a key role in the pathogenesis of the inflammatory bowel disease (IBD). Bactericidal/permeability increasing protein (BPI) has an important role in the recognition and neutralization of gram-negative bacteria by host innate immune system. The polymorphism on BPI gene called Lys216Glu is on the suspected list of IBD pathogenesis.
URI
http://hdl.handle.net/20.500.12627/36973
https://doi.org/10.1016/j.crohns.2010.08.008
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