Effects of partial liquid ventilation on gas exchange and lung mechanics in healthy animals

Abstract

Partial liquid ventilation with perfluorocarbon liquids has been shown to improve pulmonary gas exchange and lung mechanics in animals with acute respiratory failure. In this study, we aimed to investigate whether healthy animals would maintain effective gas exchange during partial liquid ventilation and, respiratory and mechanical properties of healthy lung would be well preserved at the long-term, following partial liquid ventilation trial.