Effect of haemodiafiltration vs conventional haemodialysis on growth and cardiovascular outcomes in children - the HDF, heart and height (3H) study
Author
Bulut, Ipek Kaplan
VIDAL, Enrico
VONDRAK, Karel
ZALOSZYC, Ariane
FISCHBACH, Michel
SCHAEFER, Franz
SCHMITT, Claus Peter
BUESCHER, Rainer
Dempster, Claire
Duzova, Ali
Hayes, Wesley
HEGDE, Shivram
KRID, Saoussen
Licht, Christoph
LITWIN, Mieczyslaw
Mayes, Mark
Mir, Sevgi
Nemec, Rose
OBRYCKI, Lukasz
PAGLIALONGA, Fabio
PICCA, Stefano
RANCHIN, Bruno
SAMAILLE, Charlotte
SHENOY, Mohan
SINHA, Manish
Yilmaz, Alev
Canpolat, Nur
Shroff, Rukshana
Bayazit, Aysun
STEFANIDIS, Constantinos J.
ASKITI, Varvara
Azukaitis, Karolis
Agbas, Ayse
Anarat, Ali
AOUN, Bilal
Bakkaloglu, Sevcan
Bhowruth, Devina
BORZYCH-DUZALKA, Dagmara
HABBIG, Sandra
Smith, Colette
SPASOJEVIC, Brankica
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Background: Cardiovascular disease is prevalent in children on dialysis and accounts for almost 30% of all deaths. Randomised trials in adults suggest that haemodiafiltration (HDF) with high convection volumes is associated with reduced cardiovascular mortality compared to high-flux haemodialysis (HD); however paediatric data are scarce. We designed the haemodiafiltration, heart and height (3H) study to test the hypothesis that children on HDF have an improved cardiovascular risk profile, growth and nutritional status and quality of life, compared to those on conventional HD.
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