Malignant Transformation of Parotid Gland Non-sebaceous Lymphadenoma: Case Report and Review of Literature
Yazar
Gulluoglu, Mine
Basaran, Bora
Sonmez, Said
Bagbudar, SİDAR
Kara, Hakan
Üst veri
Tüm öğe kaydını gösterÖzet
Non-sebaceous lymphadenoma is a sporadic benign tumor of salivary glands. Histopathologic and immunohistochemical properties, diagnostic criteria, and theories for the histologic origin of the disease have been defined and well-discussed in the literature. However, none of the cases showed malignant transformation to date. We reported a case of 54 years old female patient with a right preauricular mass. Magnetic resonance imaging demonstrated a 2 cm, well-defined contrast-enhanced mass in the right parotid gland. Fine needle aspiration cytology was undiagnostic but suspicious for malignancy. Total parotidectomy with facial nerve preservation was done. In the histopathological examination, non-sebaceous lymphadenoma regions and malignant cells with abundant cytoplasm, large vesicular nuclei, and prominent nucleoli, which occupied approximately 70% of the mass, were seen. The diagnosis was undifferentiated carcinoma arisen from non-sebaceous lymphadenoma. Adjuvant radiotherapy was given. No recurrence was detected during ten months of follow-up. This case is the first case of a malignancy developed from non-sebaceous lymphadenoma.
Bağlantı
http://hdl.handle.net/20.500.12627/34565https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85078739631&origin=inward
https://doi.org/10.1007/s12105-020-01133-3
Koleksiyonlar
- Makale [92796]