Idiopathic portal hypertension during a catastrophic attack in a patient with primary antiphospholipid syndrome.

Abstract

A 43-year old male patient with hyponatremic hypertensive syndrome was diagnosed as catastrophic primary antiphospholipid syndrome (PAPS). He subsequently developed hepatosplenomegaly. The patient also carried thrombophilia- and haemochromatosis-associated gene mutations. Further investigations upon persistence of splenomegaly indicated development of idiopathic portal hypertension. (Acta gastroenterol. belg., 2010, 73, 521-526).