The effects of periodontal therapy on intracrevicular prostaglandin E-2 concentrations and clinical parameters in pregnancy

Abstract

Background: The increase in circulating levels of progesterone during pregnancy stimulates production of prostaglandins, especially prostaglandin E-2, possibly resulting in pregnancy gingivitis. The purpose of this study is to evaluate the influence of prostaglandin E-2 concentrations on gingival tissues in pregnancy and to assess its relationship to clinical parameters.