Electrochemical Determination of Nicotine Poly (Alizarin red S) Modified Graphene Screen-Printed Carbon Electrode

Abstract

Background: The electrochemical determination of nicotine was investigated at the poly (alizarin red S) modified graphene/screen printed carbon electrode (poly (ARS)-GR/SPCE). The peak value of nicotine at poly (ARS)-GR/SPCE was increased comparing with the unmodified GR/SPCE, suggesting that the disposable GR/SPCE was efficiently modified by poly (ARS) to fabricate the good working area. Characterization of the modified electrode was realized with electrochemical impedance spectroscopy and scanning electron microscopy. Under ideal experimental conditions, differential pulse voltammetry of nicotine showed oxidation at +600 mV (vs. Ag/AgCl) in phosphate buffer solution pH 7.0.