Determination of Corrected QT Interval in Kangal Breed Dogs

Abstract

QT interval is one of the important reasons of severe and life threatening ventricular arrhythmias in humans and animals Many formulas have been developed for correcting the QT interval however the best formula did not define yet by the researchers. For this reason, forty-nine clinically healthy Kangal dogs without cardiac problems other than sinus arrhythmia were included to the study. In this study corrected QT interval was determined by Bazet (QTcB = QT/root RR), Fridericia (QTcF = QT/(3)root RR), Famingham (QT+0.154(1-RR)), Van der Water (QTcVdW = QT-0.087((60/HR)-1)), Hodges (QT+0.00175(HR-60)), Matsunaga (QTcM = log600 QT/logRR) formulas. As a result, Bazett's formula showed the best consistency because the slope curve of the regression line was closest to zero (-0.00743) in our study. (C) 2018 PVJ. All rights reserved