Polymorphisms in the endothelial nitric oxide synthase gene are associated with Behcet's disease

Abstract

Objective. Reduced plasma nitric oxide (NO) levels in Behcet's disease (BD) patients have been implicated in the development of the endothelial abnormalities and thrombotic complications occurring in these patients. This study investigated the association of the endothelial NO Synthase (eNOS) gene polymorphisms with BD.