Antibiotics resistance

Abstract

The treatment of bacterial infections is very complicated by the ability of bacteria to develop resistance to antimicrobial agents. Bacterial resistance results in treatment failure, inadequate empiric antibacterial therapy, the spread of resistant bacteria within the hospital and community, prolonged hospital stay, and mortality. This article presents a brief overview of the problem of bacterial resistance and examines the mechanisms of action of commonly used antibacterial drugs and the mechanisms that bacteria have developed to overcome them. (Turk Arch Ped 2010; 45: 80(th) Year: 45-9)