Dual-role of beta borophene nanosheets as highly effective antibacterial and antifungal agent

Abstract

Antimicrobial resistance toward antibiotics has been a serious clinical problem to current bacterial infections therapy. In this context, current research and development have been focused on developing new perspectives on two-dimensional (2D) materials based antimicrobial agents. With the rapid development of 2D borophene, it has been regarded as a promising agent for sensor, energy, and biomedical applications. Herein, we have reported the fabrication of the multifunctional antibacterial and antifungal agent, beta-rhombohedral crystalline structured borophene nanosheets, which were prepared using a top-down synthesis approach. The antibacterial and antifungal activities of beta borophene nanosheets were investigated to determine using different pathogenic microorganisms such as Staphylococcus aureus (NCTC 10788/Lot 0350520029), Pseudomonas aureginosa (ATCC 9027/Lot 3270513), Escherichia coli (ATCC 8739/Lot 4835151), Candida albicans (NCPF 3179/Lot040920020), and Aspergillus brasilliensis (NCPF 2275/Lot 020620065) using the total aerobic mesophilic microorganism (lSO 21149) and mold-yeast (lSO 16212) guidelines. According to the experimental results, we showed that the borophene nanosheets had an effectively inhibitory activity against several medically serious bacterial and fungal pathogenic microorganisms.