Evaluation of cognitive functions and the related factors in 50-80 year type 2 diabetic subjects

Abstract

To study cognitive functions in 50-80 year aged type 2 diabetic patients. Cognitive performance was evaluated through a mini mental test (MMT) in 131 patients between 50 and 80 years (100 type 2 diabetics and 31 non-diabetics). Relation analysis were carried out for different parameters. Scores in registration and recall were significantly lower in diabetic group. The effect of HbA1c, body mass index (BMI) and age variables on MMT score was statistically significant. A negative linear correlation was estimated between MMT score and age, HbA1c level and BMI value. HbA1c, age and BMI were inversely related to cognitive functions. MMT scores were 24.98 +/- 3.10 in diabetic group and 25.35 +/- 3.22 in control group and statistically no significant difference was found. No significant difference was between type 2 diabetics and non-diabetics in terms of cognitive functions. But performance of diabetic patients in relation to the registration and recall was lower. Poor glycemic control and obesity in diabetics negatively affect cognitive performance.