Urine macrophage migration inhibitory factor levels in children with renal scarring due to recurrent urinary tract infections

Abstract

Objective: Macrophage migration inhibitory factor (MIF) is a pleiotropic proinflammatory cytokine that plays an important role in several disease including sepsis, pneumonia, diabetes, rheumatoid arthritis, inflammatory bowel disease and cancer. In this study, our aim was to examine the levels of macrophage migration inhibitory factor in children with renal scarring due to recurrent urinary tract infection.