The effect of 1,25-dihydroxyvitamin D3 on liver damage, oxidative stress, and advanced glycation end products in experimental nonalcoholic- and alcoholic- fatty liver disease
Tarih
2021Yazar
Dogan-Ekici, Isin
Dogru-Abbasoglu, Semra
Kucukgergin, Canan
Uysal, Mujdat
Bingul, Ilknur
Aydin, A. Fatih
Üst veri
Tüm öğe kaydını gösterÖzet
Background/aim: Oxidative stress and advanced glycation end products (AGEs) formation are proposed as effective mechanisms in the pathogenesis of nonalcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD). 1,25(OH)(2)D-3 was proposed to have antioxidant, antiinflammatory and antiglycation properties. In this study, the effect of 1,25(OH)(2)D-3 treatment on oxidative stress parameters and AGEs levels together with hepatic histopathology was investigated in high fructose (HFr) or ethanol (EtOH)-treated rats.
Koleksiyonlar
- Makale [92796]