• Türkçe
    • English
  • English 
    • Türkçe
    • English
  • Login
View Item 
  •   Home
  • Avesis
  • Dokümanı Olmayanlar
  • Bildiri
  • View Item
  •   Home
  • Avesis
  • Dokümanı Olmayanlar
  • Bildiri
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Determination of fluconazole susceptibility in Schizosaccharomyces pombe

Author
Uçar, Yasemin
Palabiyik, Bedia
Kurt, Ezgi
Kartal Sural, Burcu
Türk, Ayşegül
Metadata
Show full item record
Abstract
Fluconazole inhibits ergosterol biosynthesis and this deficiency prevents fungal growth by disrupting the structure of the fungal cell membrane. 3 42 genes that were fully sensitive and 33 genes that were semi-sensitive to 50 µg/ml fluconazole, 11 genes sensitive to 25 µg/ml and 3 genes sensitive to 10 µg/ml fluconazole were identified. Three common genes were identified that were sensitive to all three doses; rpl2301, rps2201 and pho7. These genes were found to play a major role in protein synthesis. As a result of Table 1, it was determined that the biological processes of the determined genes showed high diversity and the lethal effect of fluconazole on cells was not dependent on a single mechanism, and as a result of Table 2, the lethal activity of fluconazole was closely related to the binding processes in the cell.
URI
http://hdl.handle.net/20.500.12627/174521
Collections
  • Bildiri [64839]

Creative Commons Lisansı

İstanbul Üniversitesi Akademik Arşiv Sistemi (ilgili içerikte aksi belirtilmediği sürece) Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

DSpace software copyright © 2002-2016  DuraSpace
Contact Us | Send Feedback
Theme by 
Atmire NV
 

 


Hakkımızda
Açık Erişim PolitikasıVeri Giriş Rehberleriİletişim
sherpa/romeo
Dergi Adı/ISSN || Yayıncı

Exact phrase only All keywords Any

BaşlıkbaşlayaniçerenISSN

Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsTypesThis CollectionBy Issue DateAuthorsTitlesSubjectsTypes

My Account

LoginRegister

Creative Commons Lisansı

İstanbul Üniversitesi Akademik Arşiv Sistemi (ilgili içerikte aksi belirtilmediği sürece) Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

DSpace software copyright © 2002-2016  DuraSpace
Contact Us | Send Feedback
Theme by 
Atmire NV