Multicentre International Study for the Prevention with iAluRil of Radio-induced Cystitis (MISTIC): A Randomised Controlled Study

Author
Minervini, Andrea
Di Maida, Fabrizio
Lunik, Richard
Colombo, Renzo
Serretta, Vincenzo
Cetinel, Bulent
Bini, Vittorio
Corradengo, Davide
Lazzeri, Massimo
Vittori, Gianni
Romancik, Martin
Sancho Pardo, Gemma
Sanguedolce, Francesco
Palou Redorta, Juan
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Abstract
Background: Radiation-induced cystitis is a common side effect of radiotherapy (RT) to the pelvic area. Hyaluronic acid (HA) and chondroitin sulfate (CS) are components of the urothelial mucosa and positive results have been obtained for intravesical HA/CS instillations for the treatment of urinary tract infections and bladder pain syndrome. HA/CS may also have a protective effect against RT bladder toxicity.
URI
http://hdl.handle.net/20.500.12627/172215
https://doi.org/10.1016/j.euros.2021.01.016
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