Association of CDH1 -160 C -> A and -347 G -> GA polymorphisms and expression of E-cadherin and gastric cancer: A case-control study

Abstract

Objective: The loss of function of the E-cadherin (CDH1) gene with -160 C -> A and -347 G -> GA polymorphisms is regarded as a critical step for gastric cancer. It was aimed to investigate possible association of these polymorphisms and immunoexpression of E-cadherin with gastric cancer.