IN VITRO ANTITUMOR EFFECTS OF A NEW CULTIVAR (GURARSLAN) OF TRIGONELLA FOENUM GRAECUM L.

Abstract

Background: The main goals of our study were as follows: (1) to investigate whether the methanolic extract of the new cultivar (Gurarslam) of Trigonella foenum graecum L. seeds exhibit antiproliferative effects on the HeLa human cervix carcinoma, Mat-LyLu rat prostate carcinoma and 3T3 embryonic mouse fibroblast cell lines, (2) to determine how mitosis and DNA synthesis are affected in cancer cells by the extract, and (3) to observe the changes in cell morphology after treatment with the extract.