The effects of a low dose of cabergoline on induction of estrus and pregnancy rates in anestrous bitches

Abstract

This is the first report of successful induction of normal estrus and ovulation in breeder bitches with as a low dose as 0.6 mu g/kg/day of cabergoline formulation marketed for use in women. Sixty-one pure breed bitches from various breeds were used in the study at their already determined periods of anestrus. Twenty-four dogs formed the control group, while 37 bitches were administered with two different doses of cabergoline (recommended dose group, n = 10, 5 mu g/kg/day and low dose group, n = 27, 0.6 mu g/kg/day). Induced estrus rates and mean treatment and proestrus durations of dogs in these two dose groups were compared.