Association of the A561C E-selectin polymorphism with systemic lupus erythematosus in 2 independent populations

Gul, A; Inanc, Murat; Ordi, J; Bruce, I; Hajeer, A; El-Magadmi, M; Alansari, A; Teh, LS

Tarih

2001

Yazar

Gul, A

Inanc, Murat

Ordi, J

Bruce, I

Hajeer, A

El-Magadmi, M

Alansari, A

Teh, LS

Üst veri

Tüm öğe kaydını göster

Özet

Objective. E-selectin is expressed on cytokine stimulated endothelial cells and plays an important role in leukocyte-endothelium interactions and inflammatory cell recruitment. The gene for E-selectin is located at chromosome 1q23-25 within the linkage area for systemic lupus erythematosus (SLE). The best characterized polymorphism in E-selectin molecule is A561C. which codes for Ser128Arg. We studied the prevalence of the A561C E-selectin gene polymorphism in patients with SLE and controls from 3 different ethnic populations.

Bağlantı

http://hdl.handle.net/20.500.12627/162095

Koleksiyonlar

Makale [92796]