RESPIRATORY AND HEMODYNAMIC-EFFECTS OF CONVENTIONAL VOLUME CONTROLLED PEEP VENTILATION, PRESSURE REGULATED VOLUME CONTROLLED VENTILATION AND LOW-FREQUENCY POSITIVE PRESSURE VENTILATION WITH EXTRACORPOREAL CARBON-DIOXIDE REMOVAL IN PIGS WITH ACUTE ARDS

Abstract

The purpose of this study was to evaluate whether any benefit of low frequency positive pressure ventilation with extracorporeal carbon dioxide removal (LFPPV-ECCO(2)R) existed over either volume controlled ventilation (VCV) with measured best-PEEP or pressure regulated volume controlled ventilation (PRVCV) with an inspiration/expiration (I/E) ratio of 4:1, with respect to arterial oxygenation, lung mechanics and haemodynamics, in acute respiratory failure.