Association between interleukin-1 beta (IL-1 ss) gene polymorphism and outcome after head injury: an early report

Abstract

Background. Recent studies focusing on the genetic influences on outcome after head injury (HI) have suggested that different alleles of certain genes are associated with different outcomes. Interleukin-1 beta (IL-1 beta) gene, especially beta 2 polymorphism, is frequently observed in Alzheimer's disease, a remarkable degenerative state in which HI is among the known risk factors. Therefore, the aim of this paper was to search for the possible association between the outcome and IL-1 beta gene polymorphism in human HI.