Sildenafil citrate inhibits agonist induced contractions in isolated rat seminal vesicles
Date
2006Author
Onur, Rahmi
Kadioglu, Ates
Tasdemir, Cemal
Ayar, Ahmet
Orhan, Irfan
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Purpose: Sildenafil is reported to regulate smooth muscle contractility through nitric oxide-cyclic guanosine monophosphate, not only in the corpus cavernosum. Its possible effects on seminal vesicle contractility might be of importance with respect to premature ejaculation. We investigated the effects of sildenafil citrate (Pfizer, New York, New York) on agonist induced isometric contractions of the rat seminal vesicle in vitro.
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- Makale [92796]