FEASIBILITY AND EFFICACY OF INDUCTION DOCETAXEL, CISPLATIN, AND 5-FLUOROURACIL CHEMOTHERAPY COMBINED WITH CISPLATIN CONCURRENT CHEMORADIOTHERAPY FOR NONMETASTATIC STAGE IV HEAD-AND-NECK SQUAMOUS CELL CARCINOMAS

Abstract

Purpose: To report the experience of treating selected fit patients with locally advanced head-and-neck squamous cell carcinoma with three cycles of induction TPF (docetaxel 75 mg/m(2), cisplatin 75 mg/m(2), 5-fluorouracil 750 mg/m(2), Days 2-5) followed by concurrent three-weekly bolus cisplatin 100 mg/m(2) chemoradiotherapy.