Association of APOE polymorphisms with disease severity in MS is limited to women
dc.contributor.author | de Andrade, M | |
dc.contributor.author | Weinshenker, BG | |
dc.contributor.author | Atkinson, EJ | |
dc.contributor.author | McMurray, CT | |
dc.contributor.author | Rodriguez, M | |
dc.contributor.author | Kantarci, OH | |
dc.contributor.author | Hebrink, DD | |
dc.contributor.author | Achenbach, SJ | |
dc.contributor.author | Pittock, SJ | |
dc.contributor.author | Altintas, A | |
dc.contributor.author | Schaefer-Klein, JL | |
dc.date.accessioned | 2021-03-06T08:01:52Z | |
dc.date.available | 2021-03-06T08:01:52Z | |
dc.date.issued | 2004 | |
dc.identifier.citation | Kantarci O., Hebrink D., Achenbach S., Pittock S., Altintas A., Schaefer-Klein J., Atkinson E., de Andrade M., McMurray C., Rodriguez M., et al., "Association of APOE polymorphisms with disease severity in MS is limited to women", NEUROLOGY, cilt.62, ss.811-814, 2004 | |
dc.identifier.issn | 0028-3878 | |
dc.identifier.other | av_defe36f5-ab39-490c-b659-c3918df21a7b | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/146899 | |
dc.identifier.uri | https://doi.org/10.1212/01.wnl.0000113721.83287.83 | |
dc.description.abstract | The authors studied the association of an exon 4 (E4* epsilon2/3/4) and three promoter polymorphisms of APOE with disease course and severity stratified by gender in 221 patients with multiple sclerosis from two overlapping population-based prevalence cohorts. Women carriers of the E4* epsilon2 allele took longer to attain an Expanded Disability Status Scale score of 6 ( p = 0.015) and had more favorable ranked severity scores than noncarriers ( p = 0.009). There was no association in men. Alleles epsilon3 or epsilon4 and promoter polymorphisms were not associated with disease course or severity. | |
dc.language.iso | eng | |
dc.subject | Nöroloji | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | KLİNİK NEUROLOJİ | |
dc.title | Association of APOE polymorphisms with disease severity in MS is limited to women | |
dc.type | Makale | |
dc.relation.journal | NEUROLOGY | |
dc.contributor.department | , , | |
dc.identifier.volume | 62 | |
dc.identifier.issue | 5 | |
dc.identifier.startpage | 811 | |
dc.identifier.endpage | 814 | |
dc.contributor.firstauthorID | 171108 |
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Makale [92796]