Oxytocin Protects Rat Skeletal Muscle Against Ischemia/Reperfusion Injury

Abstract

Background: Oxytocin (OXY) is a well-known nonapeptide that functions in reproduction. It is also known as an antioxidant in several organs. However, little is about its role in the protection of tissue against ischemiareperfusion injury in skeletal muscle. The aim of this study was to evaluate the protective and therapeutic antioxidant effect of oxytocin in skeletal muscle during ischemiareperfusion (IR) injury.