Prognostic significance of the TEL-AML1 fusion gene in pediatric acute lymphoblastic leukemia in Turkey

Date
2003
Author
Timur, C
Sirma, S
Devecioglu, O
Meral, A
Gedikoglu, G
Ozbek, U
Agaoglu, L
Yuksel, L
Anak, S
Yildiz, I
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Abstract
Purpose: The t(12;21) translocation is the most common reciprocal chromosomal rearrangement in pediatric acute lymphoblastic leukemia (ALL). This translocation fuses two genes, TEL and AML1, and results in the production of the TEL-AML1 fusion protein. The authors investigated the incidence and prognostic significance of the TEL-AML1 fusion gene in patients with ALL in Turkey.
URI
http://hdl.handle.net/20.500.12627/14475
https://doi.org/10.1097/00043426-200303000-00005
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