Association between clinical and pathological findings in pediatric onset IBD patients, a retrospective anaylsis from a tertiary center

Abstract

We aimed to investigate the difference between 3 age groups of IBD (younger than 2 years of age, 2-10 years and 10-17 years of age) as a retrospective analysis. We included symptoms, lab results, colonoscopic and histopathological findings which are followed in a tertiary center. We performed a retrospective analysis of data collected from 71 children (0-17 years old) with pediatric IBD between 2003 and 2016. We classified patients according to the Pediatric Paris modification of the Montreal classifications and compared age of the symptom‟s onset and diagnosis, the first presentation of patients, clinical, laboratory and imaging findings of them. 6 patients had infantile onset IBD (younger than 2 years of age), 19 had Early onset IBD, EOIBD, (younger than 10 years of age) and 45 had Pediatric onset IBD (younger than 17 years of age). Among this children, time between the first symptoms and the diagnosis ranged between 1 and 76 months with mean being 12.69 ± 16.02 months. In 81% of the children fecal calprotectin was measured and 10% of these was less than 50 μg/g, 15% was between 50-200 μg/g, and 75% was greater than 200 μg/g.