Superior consistency of ambulatory blood pressure monitoring in children: implications for clinical trials
Tarih
2009Yazar
Dusek, Jiri
Emre, Sevinc
Gellermann, Jutta
Jankauskiene, Augustina
Schaefer, Franz
Gimpel, Charlotte
Wuehl, Elke
Arbeiter, Klaus
Drozdz, Dorota
Trivelli, Antonella
Charbit, Marina
Üst veri
Tüm öğe kaydını gösterÖzet
Background Casual office blood pressure (CBP) measurements are still standard in antihypertensive drug trials. In pediatric hypertensive trials, ethical considerations, very low disease prevalence and the marked impact of white-coat hypertension create the need for very sensitive and reproducible techniques of BP assessment. We hypothesized that ambulatory BP monitoring (ABPM) may identify treatment effects more sensitively than CBP and thereby reduce sample sizes required in pediatric antihypertensive trials.
Koleksiyonlar
- Makale [92796]