Impact of fingolimod on CD4+T cell subset and cytokine profile of relapsing remitting multiple sclerosis patients

Author
Otunc, Gokturk
Gunduz, Tuncay
Icoz, Sema
Tuzun, Erdem
Akcay, Halil Ibrahim
Turkoglu, Recai
Altunrende, Burcu
Kasap, Mithat
Eraksoy, Mefkure
Cinar, Suzan
Kurtuncu, Murat
Ulusoy, Canan Aysel
Yilmaz, Vuslat
Caliskan, Zeynep
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Abstract
Fingolimod inhibits the egress of lymphocytes from lymphatic tissues and also directly affects their functions by modulation of the sphingosine-1 -phosphate receptor 1 (S1P1). Our aim was to evaluate the impact of fingolimod on diverse CD4+ T cell subsets, and cytokines.
URI
http://hdl.handle.net/20.500.12627/140644
https://doi.org/10.1016/j.jneuroim.2019.577065
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