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Coronary flow reserve is impaired in patients with adult growth hormone (GH) deficiency

Date
2007
Author
Demirturk, Mustafa
CIMEN, Arif Oğuzhan
Onur, Imran
Sen, FATMA
Elitok, Ali
KORKMAZ, Semra
KUTLUTURK, Faruk
OZBEY, Nese
PAMUKCU, Burak
Kasikcioglu, Erdem
Oflaz, Hüseyin
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Abstract
Objective Relationship between adult growth hormone deficiency (AGHD) and increased cardiovascular disease risk is very well known in hypopituitary patients treated with conventional hormone replacement therapy other than growth hormone (GH) administration. Endothelial dysfunction, an early and reversible event in pathogenesis of atherosclerosis, is associated with increased vascular smooth muscle tone, arterial stiffening and intima-media thickness (IMT). Coronary flow reserve (CFR) measurement by transthoracic Doppler echocardiography (TTDE) reflects coronary microvascular and endothelial functions, as a cheaper and an easy screening test. We have used TTDE to evaluate endothelial function and coronary microvascular function in AGHD.
URI
http://hdl.handle.net/20.500.12627/138383
https://doi.org/10.1111/j.1365-2265.2007.02767.x
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Creative Commons Lisansı

İstanbul Üniversitesi Akademik Arşiv Sistemi (ilgili içerikte aksi belirtilmediği sürece) Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

DSpace software copyright © 2002-2016  DuraSpace
Contact Us | Send Feedback
Theme by 
Atmire NV