DIFFERENT EFFECTS OF CAV1 rs3807990 VARIATION ON LIPID PROFILE IN PATIENTS WITH CORONARY HEART DISEASE BASED ON PRESENCE OF DIABETES
Date
2020Author
Ilikay, Serap
Ozturk, Oguz
Aydogan, Hulya Yilmaz
Bugra, Zehra
Kurnaz-Gomleksiz, Ozlem
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Objective: A decreased antiatherogenic function of endothelium causes endothelial dysfunction characterized by decreased nitric oxide (NO) levels. NO amounts can be regulated by the inhibition of eNOS enzyme activity via caveolin-1 (Cav-1). We aimed to determine the effect of CAV1 rs3807990 on metabolic and lipid biomarker levels in diabetic and non-diabetic coronary heart disease (CHD) and to determine the possible contribution to diabetic dyslipidemia.
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